가토 하치조신경 재생에 있어 Lerve Growth Factor의 효과
Effect of nerve growht factor in regeneration of mandibular nerve of rabbit
박광, 김현태, 이종호,
소속 상세정보
박광 ( ) - 광주보훈병원
김현태 ( ) - 광주보훈병원
이종호 ( ) - 광주보훈병원
KMID : 0360119960180020261
Abstract
An experimental study was performed to evaluate the efficacy of nerve growth factor(NGF) on inferior alveolar nerve in a rabbit model. In 20 New Zealand white rabbits. 14mm of bilat eral alveolar nerve were resected and the defects were repaired
with
the 17 mm silicone conduits. In group I, 5mm autologous nerve segment were located centrally in the left side after tubulization and NGF solution(Sigma chemical 0.1 mg/mL) was instilled into each conduit. In group II, nerve repair modality was
the
same
but no NGF solution was instilled into the conduits. On 2 months and 6 months postoperatively, the results were evaluated by clinical and hist omorphometric assessment.
The result was that autologous nerve segment group show the best nerve regeneration effect and NGF instilled group the worst.
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